Heart Rate Dynamics Predict Anaesthetic Depth: A Compact Machine Learning Model

Withholding versus Continuing Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers Before Noncardiac Surgery in Older Patients: A Multicenter, Randomized, Double-Blind Trial

Effect of Preoperative Casual Physical Exercise on Postoperative Delirium in Asymptomatic Cerebral Infarction Patients: A Prospective Multicenter Cohort Study

Mediating Effect of Postoperative Acute Pain on Preoperative Subacute/Chronic Pain and 1-Year Postoperative Cognitive Trajectory: Mediation Analysis Based on China Surgery Anesthesia Cohort

Metabolic syndrome and the risk of perioperative ischemic stroke in non-cardiac surgery: a case-control retrospective study

Effects of Transcutaneous Acupoint Electrical Stimulation on Postoperative Delirium and EEG Parameters in Elderly Abdominal Surgery Patients

Dynamic Correlation Between Exhaled Propofol Concentration via VUV-TOF MS and BIS for Predicting Delayed Emergence in General Anesthesia

Brain Network Signatures of Desflurane-Induced Loss of Consciousness

Application of COMBO Endoscopy-Specific Oropharyngeal Airway in Obese Patients Undergoing Sedative Gastrointestinal Endoscopy: A Simon's Two-Stage Trial

Impact of Noise Exposure During General Anesthesia Emergence on Acute Postoperative Pain in Orthopedic Surgery: A Prospective Observational Study

No Association Between Glaucoma and Stroke Risk: Insights From a Cross-Sectional Study and Two-Sample Mendelian Randomization Analysis

METTL14 integrates tumor-derived SAM to drive pain–depression comorbidity in PDAC via epigenetic rewiring of parabrachial circuits

Impaired BCAA Catabolism in Macrophages Exacerbates Sepsis-Induced Lung Injury by Activating Mitochondria AGEs and mtDNA Release

Study on the mechanism of Perioperative Neurocognitive Disorder induced by Plin4-mediated lipid droplets accumulating in oligodendrocytes based on Single-nucleus RNA-seq and Spatial Transcriptomics

TGM1 Modulates VPL(TGM1)-S1HL(CaMKIIα) Circuitry via Wnt3a/β-Catenin Signaling Pathway in Central Post-Stroke Pain

Hypothalamic-Midbrain Neural Circuit Mechanism Underlying Preoperative Sleep Pressure-Induced Postoperative Hyperalgesia

SNAPR Neurons: A Novel Spinal-to-RVM Projection Pathway Modulating Pain Threshold

A brainstem-thalamic-cortex glutaminergic neuron pathway modulates propofol anesthesia

Pseudolongum Bifidobacterium Regulates Acetate Metabolism to Alleviate Neuronal PANoptosis and Cognitive Dysfunction in Intermittent Hypoxia Mice

Neonatal Esketamine Anesthesia Exposure Enhances Microglial Synaptic Pruning Function Leading to Adolescent Social Deficits

NRG-1 Attenuates Neuromuscular Dysfunction in ICUAW Model Mice via PGC-1α/GABP Pathway: Mechanism Study

Sevoflurane Alleviates Septic ARDS by Targeting CD177 hi Neutrophils to Regulate cGAS-STING-NETs Axis: Single-Cell Sequencing and Clinical Cohort Study

Semaglultide targets Spp1+ microglia/macrophage to attenuate neuroinflammation following perioperative stroke

Innovating Patient-Centered Comfort Care to Drive High-Value Hospital Development

Innovative Anesthesia Management Guided by Qidian Medical Philosophy: Clinical Practice

Breakthrough Approaches in Diagnosis and Therapeutics of sleep disturbance

Analgesia and Sedation Management by Anesthesiologists in Hospice and Palliative Care

Perioperative Oxygen Therapy: Current Evidence and Unresolved Controversies

Mechanisms of DHEA Attenuating PND via Inhibiting Abnormal Microglial Mitochondrial Fission

Esketamine: Novel Hope Against Post-Surgical Sleep Disruption in the Elderly